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Total Synthesis Provides Strong Evidence: Xestocyclamine A is the Enantiomer of Ingenamine

[Image: see text] Xestocyclamine A ((−)-1) is featured prominently in a biosynthesis pathway leading to a large family of polycyclic alkaloids. The first total synthesis now proves that the structure of this compound had originally been misassigned. The route to (−)-1 is based on a double Michael ad...

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Publicat a:J Am Chem Soc
Autors principals: Meng, Zhanchao, Fürstner, Alois
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467676/
https://ncbi.nlm.nih.gov/pubmed/32544329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c05347
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