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Proline metabolism and cancer

Proline plays a special role in cancer metabolism. Proline oxidase (POX), a.k.a. proline dehydrogenase (PRODH), is among a few genes induced rapidly and robustly by P53, the tumor suppressor. Ectopic expression of POX under control of tet-off promoter initiated mitochondrial apoptosis. The mechanism...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Biosci (Landmark Ed)
Auteurs principaux: Phang, James M., Liu, Wei
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467630/
https://ncbi.nlm.nih.gov/pubmed/22201839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2741/4022
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