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Optimising efficacy of antibiotics against systemic infection by varying dosage quantities and times

Mass production and use of antibiotics has led to the rise of resistant bacteria, a problem possibly exacerbated by inappropriate and non-optimal application. Antibiotic treatment often follows fixed-dose regimens, with a standard dose of antibiotic administered equally spaced in time. But are such...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Hoyle, Andy, Cairns, David, Paterson, Iona, McMillan, Stuart, Ochoa, Gabriela, Desbois, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467302/
https://ncbi.nlm.nih.gov/pubmed/32745111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008037
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