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Potentiating aminoglycoside antibiotics to reduce their toxic side effects

The lack of new antibiotics necessitates the improvement of existing ones, many of which are limited by toxic side effects. Aminoglycosides, antibiotics with excellent activity and low bacterial resistance, are hampered by dose-dependent toxic effects in patients (nephrotoxicity, ototoxicity). High...

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Pubblicato in:PLoS One
Autori principali: Rosenberg, Christopher R., Fang, Xin, Allison, Kyle R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467299/
https://ncbi.nlm.nih.gov/pubmed/32877437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237948
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