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D-Penicillamine prolongs survival and lessens copper-induced toxicity in Drosophila melanogaster

D-penicillamine (DPA) is an amino-thiol that has been established as a copper chelating agent for the treatment of Wilson’s disease. DPA reacts with metals to form complexes and/or chelates. Here, we investigated the survival rate extension capacity and modulatory role of DPA on Cu(2+)-induced toxic...

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Publicat a:Toxicol Res (Camb)
Autors principals: Abolaji, Amos Olalekan, Fasae, Kehinde Damilare, Iwezor, Chizim Elizabeth, Farombi, Ebenezer Olatunde
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467227/
https://ncbi.nlm.nih.gov/pubmed/32905187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxres/tfaa032
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