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Beyond Cell Death: New Functions for TNF-family Cytokines in Autoimmunity and Tumor Immunotherapy

Originally discovered as an inducer of apoptosis, the TNF-family receptor Fas (CD95, APO-1, TNFRSF6) has more recently been found to have functions beyond cell death, including T cell co-stimulation and promoting terminal differentiation of CD4(+) and CD8(+) T cells. Other TNF-family members also di...

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Detalhes bibliográficos
Publicado no:Trends Mol Med
Main Authors: Yi, Fei, Frazzette, Nicholas, Cruz, Anthony, Klebanoff, Christopher, Siegel, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7466867/
https://ncbi.nlm.nih.gov/pubmed/29880309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2018.05.004
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