Promoter methylation, transcription, and retrotransposition of LINE-1 in colorectal adenomas and adenocarcinomas

BACKGROUND: The methylation of the CpG islands of the LINE-1 promoter is a tight control mechanism on the function of mobile elements. However, simultaneous quantification of promoter methylation and transcription of LINE-1 has not been performed in progressive stages of colorectal cancer. In additi...

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Vydáno v:Cancer Cell Int
Hlavní autoři: Shademan, Milad, Zare, Khadijeh, Zahedi, Morteza, Mosannen Mozaffari, Hooman, Bagheri Hosseini, Hadi, Ghaffarzadegan, Kamran, Goshayeshi, Ladan, Dehghani, Hesam
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Primary Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7466817/
https://ncbi.nlm.nih.gov/pubmed/32905102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01511-5
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