Loss of HES-1 Expression Predicts a Poor Prognosis for Small Intestinal Adenocarcinoma Patients

Objective: Hairy and enhancer of split-1 (HES-1), which is a downstream target of the Notch signaling pathway, has been linked to KRAS mutations. HES-1 has been proposed as harboring oncogenic activity in colorectal cancer but has not been investigated in adenocarcinoma of the small intestine, where...

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Vydáno v:Front Oncol
Hlavní autoři: Kim, Jeong Won, Jun, Sun-Young, Ylaya, Kris, Chang, Hee-Kyung, Oh, Young-Ha, Hong, Seung-Mo, Chung, Joon-Yong, Hewitt, Stephen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7466551/
https://ncbi.nlm.nih.gov/pubmed/32974155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01427
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