Targeting Endothelial Dysfunction in Eight Extreme-Critically Ill Patients with COVID-19 Using the Anti-Adrenomedullin Antibody Adrecizumab (HAM8101)

Recently, the stabilization of the endothelium has been explicitly identified as a therapeutic goal in coronavirus disease 2019 (COVID-19). Adrecizumab (HAM8101) is a first-in-class humanized monoclonal anti-Adrenomedullin (anti-ADM) antibody, targeting the sepsis- and inflammation-based vascular an...

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Veröffentlicht in:Biomolecules
Hauptverfasser: Karakas, Mahir, Jarczak, Dominik, Becker, Martin, Roedl, Kevin, Addo, Marylyn M., Hein, Frauke, Bergmann, Andreas, Zimmermann, Jens, Simon, Tim-Philipp, Marx, Gernot, Lütgehetmann, Marc, Nierhaus, Axel, Kluge, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465983/
https://ncbi.nlm.nih.gov/pubmed/32796765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10081171
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