Cotinine and 6-Hydroxy-L-Nicotine Reverses Memory Deficits and Reduces Oxidative Stress in Aβ(25-35)-Induced Rat Model of Alzheimer’s Disease

The nicotinic derivatives, cotinine (COT), and 6-hydroxy-L-nicotine (6HLN), showed promising cognitive-improving effects without exhibiting the nicotine’s side-effects. Here, we investigated the impact of COT and 6HLN on memory impairment and the oxidative stress in the Aβ(25-35)-induced rat model o...

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Publicado en:Antioxidants (Basel)
Autores principales: Boiangiu, Razvan Stefan, Mihasan, Marius, Gorgan, Dragos Lucian, Stache, Bogdan Alexandru, Petre, Brindusa Alina, Hritcu, Lucian
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465470/
https://ncbi.nlm.nih.gov/pubmed/32824768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9080768
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