Multiple Myeloma-Derived Extracellular Vesicles Induce Osteoclastogenesis through the Activation of the XBP1/IRE1α Axis

Bone disease severely affects the quality of life of over 70% of multiple myeloma (MM) patients, which daily experience pain, pathological fractures, mobility issues and an increased mortality. Recent data have highlighted the crucial role of the endoplasmic reticulum-associated unfolded protein res...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Raimondi, Lavinia, De Luca, Angela, Fontana, Simona, Amodio, Nicola, Costa, Viviana, Carina, Valeria, Bellavia, Daniele, Raimondo, Stefania, Siragusa, Sergio, Monteleone, Francesca, Alessandro, Riccardo, Fini, Milena, Giavaresi, Gianluca
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465175/
https://ncbi.nlm.nih.gov/pubmed/32759820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082167
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