Characterization of the DNAM-1, TIGIT and TACTILE Axis on Circulating NK, NKT-Like and T Cell Subsets in Patients with Acute Myeloid Leukemia

Background: Acute myeloid leukemia (AML) remains a major clinical challenge due to poor overall survival, which is even more dramatic in elderly patients. TIGIT, an inhibitory receptor that interacts with CD155 and CD112 molecules, is considered as a checkpoint in T and NK cell activation. This rece...

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Published in:Cancers (Basel)
Main Authors: Valhondo, Isabel, Hassouneh, Fakhri, Lopez-Sejas, Nelson, Pera, Alejandra, Sanchez-Correa, Beatriz, Guerrero, Beatriz, Bergua, Juan M., Arcos, Maria Jose, Bañas, Helena, Casas-Avilés, Ignacio, Sanchez-Garcia, Joaquin, Serrano, Josefina, Martin, Carmen, Duran, Esther, Alonso, Corona, Solana, Rafael, Tarazona, Raquel
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464787/
https://ncbi.nlm.nih.gov/pubmed/32764229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082171
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