Myelomonocytic Skewing In Vitro Discriminates Subgroups of Patients with Myelofibrosis with A Different Phenotype, A Different Mutational Profile and Different Prognosis

Normal hematopoietic function is maintained by a well-controlled balance of myelomonocytic, megaerythroid and lymphoid progenitor cell populations which may be skewed during pathologic conditions. Using semisolid in vitro cultures supporting the growth of myelomonocytic (CFU-GM) and erythroid (BFU-E...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Geissler, Klaus, Gisslinger, Bettina, Jäger, Eva, Jäger, Roland, Schiefer, Ana-Iris, Bogner, Edith, Fuchs, Elisabeth, Schischlik, Fiorella, Alpar, Donat, Simonitsch-Klupp, Ingrid, Kralovics, Robert, Gisslinger, Heinz
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464756/
https://ncbi.nlm.nih.gov/pubmed/32824053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082291
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