Distinct conformational states of SARS-CoV-2 spike protein

Intervention strategies are urgently needed to control the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pandemic. The trimeric viral spike (S) protein catalyzes fusion between viral and target cell membranes to initiate infection. Here we report two cryo-EM structures, derived from a...

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Publicat a:Science
Autors principals: Cai, Yongfei, Zhang, Jun, Xiao, Tianshu, Peng, Hanqin, Sterling, Sarah M., Walsh, Richard M., Rawson, Shaun, Rits-Volloch, Sophia, Chen, Bing
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464562/
https://ncbi.nlm.nih.gov/pubmed/32694201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abd4251
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