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Synthesis and Cytotoxic Activity of Novel C-23-Modified Asiatic Acid Derivatives

We selectively oxidized the C-23 hydroxyl group in an asiatic acid (AA) derivative and then, for the first time with AA, modification of the C-23 carboxyl group was conducted to synthesize a series of new AA derivatives. The evaluation of their cytotoxic activities against two human cancer cell line...

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Publicat a:Molecules
Autors principals: Lu, Yi-hong, Chen, Ming-cang, Liu, Fang, Xu, Zhou, Tian, Xiao-ting, Xie, Yang, Huang, Cheng-gang
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464201/
https://ncbi.nlm.nih.gov/pubmed/32823913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25163709
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