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Adenosine Receptor Agonists Increase the Inhibition of Platelet Function by P2Y(12) Antagonists in a cAMP- and Calcium-Dependent Manner

We have shown previously that platelet activity can be lowered through the simultaneous inhibition of P2Y(12) receptor and activation of adenosine receptors (AR). This work explores this concept by testing the antiplatelet potential of nine AR agonists in combination with P2Y(12) receptor antagonist...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Wolska, Nina, Kassassir, Hassan, Luzak, Boguslawa, Watala, Cezary, Rozalski, Marcin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464091/
https://ncbi.nlm.nih.gov/pubmed/32752089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13080177
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