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CYP3A Excipient-Based Microemulsion Prolongs the Effect of Magnolol on Ischemia Stroke Rats

Magnolol, which is a CYP3A substrate, is a well-known agent that can facilitate neuroprotection and reduce ischemic brain damage. However, a well-controlled release formulation is needed for the effective delivery of magnolol due to its poor water solubility. In this study, we have developed a formu...

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Détails bibliographiques
Publié dans:Pharmaceutics
Auteurs principaux: Guo, Jiun-Wen, Chien, Chih-Cheng, Chen, Jiann-Hwa
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464078/
https://ncbi.nlm.nih.gov/pubmed/32764430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12080737
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