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Impact of Host, Lifestyle and Environmental Factors in the Pathogenesis of MPN
Philadelphia-negative myeloproliferative neoplasms (MPNs) occur when there is over-production of myeloid cells stemming from hematopoietic stem cells with constitutive activation of JAK/STAT signaling, with JAK2(V617F) being the most commonly occurring somatic driver mutation. Chronic inflammation i...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7463688/ https://ncbi.nlm.nih.gov/pubmed/32722135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082038 |
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