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Ex Vivo Models Simulating the Bone Marrow Environment and Predicting Response to Therapy in Multiple Myeloma

Multiple myeloma (MM) remains incurable despite the abundance of novel drugs. As it has been previously shown, preclinical 2D models fail to predict disease progression due to their inability to simulate the microenvironment of the bone marrow. In this review, we focus on 3D models and present all c...

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Podrobná bibliografie
Vydáno v:Cancers (Basel)
Hlavní autoři: Papadimitriou, Konstantinos, Kostopoulos, Ioannis V., Tsopanidou, Anastasia, Orologas-Stavrou, Nikolaos, Kastritis, Efstathios, Tsitsilonis, Ourania E., Dimopoulos, Meletios A., Terpos, Evangelos
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463609/
https://ncbi.nlm.nih.gov/pubmed/32707884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082006
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