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TIF1 Proteins in Genome Stability and Cancer

Genomic instability is a hallmark of cancer cells which results in excessive DNA damage. To counteract this, cells have evolved a tightly regulated DNA damage response (DDR) to rapidly sense DNA damage and promote its repair whilst halting cell cycle progression. The DDR functions predominantly with...

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Detalles Bibliográficos
Publicado en:Cancers (Basel)
Main Authors: McAvera, Roisin M., Crawford, Lisa J.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463590/
https://ncbi.nlm.nih.gov/pubmed/32731534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082094
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