Increasing the Affinity of an O‐Antigen Polysaccharide Binding Site in Shigella flexneri Bacteriophage Sf6 Tailspike Protein

Broad and unspecific use of antibiotics accelerates spread of resistances. Sensitive and robust pathogen detection is thus important for a more targeted application. Bacteriophages contain a large repertoire of pathogen‐binding proteins. These tailspike proteins (TSP) often bind surface glycans and...

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Publicat a:Chemistry
Autors principals: Kunstmann, Sonja, Engström, Olof, Wehle, Marko, Widmalm, Göran, Santer, Mark, Barbirz, Stefanie
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463171/
https://ncbi.nlm.nih.gov/pubmed/32189378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202000495
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