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Increasing the Affinity of an O‐Antigen Polysaccharide Binding Site in Shigella flexneri Bacteriophage Sf6 Tailspike Protein

Broad and unspecific use of antibiotics accelerates spread of resistances. Sensitive and robust pathogen detection is thus important for a more targeted application. Bacteriophages contain a large repertoire of pathogen‐binding proteins. These tailspike proteins (TSP) often bind surface glycans and...

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Bibliografiske detaljer
Udgivet i:Chemistry
Main Authors: Kunstmann, Sonja, Engström, Olof, Wehle, Marko, Widmalm, Göran, Santer, Mark, Barbirz, Stefanie
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463171/
https://ncbi.nlm.nih.gov/pubmed/32189378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202000495
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