Atypical fibroxanthoma and pleomorphic dermal sarcoma harbor frequent NOTCH1/2 and FAT1 mutations and similar DNA copy number alteration profiles

Atypical fibroxanthomas and pleomorphic dermal sarcomas are tumors arising in sun-damaged skin of elderly patients. They have differing prognoses and are currently distinguished using histological criteria, such as invasion of deeper tissue structures, necrosis and lymphovascular or perineural invas...

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Publicado en:Mod Pathol
Main Authors: Griewank, Klaus G, Wiesner, Thomas, Murali, Rajmohan, Pischler, Carina, Müller, Hansgeorg, Koelsche, Christian, Möller, Inga, Franklin, Cindy, Cosgarea, Ioana, Sucker, Antje, Schadendorf, Dirk, Schaller, Jörg, Horn, Susanne, Brenn, Thomas, Mentzel, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463132/
https://ncbi.nlm.nih.gov/pubmed/29099504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2017.146
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