Ibuprofen mediates histone modification to diminish cancer cell stemness properties via a COX2-dependent manner

BACKGROUND: The anticancer potential of ibuprofen has created a broad interest to explore the clinical benefits of ibuprofen in cancer therapy. However, the current understanding of the molecular mechanisms involved in the anticancer potential of ibuprofen remains limited. METHODS: Cancer stemness a...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Shen, Wenzhi, Zhang, Xiaoyuan, Du, Renle, Gao, Wenjuan, Wang, Juan, Bao, Yonghua, Yang, Wancai, Luo, Na, Li, Jianjun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463005/
https://ncbi.nlm.nih.gov/pubmed/32528119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0906-7
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