Differential contribution of bone marrow-derived infiltrating monocytes and resident macrophages to persistent lung inflammation in chronic air pollution exposure

Chronic exposure to particulate matter < 2.5µ (PM(2.5)) has been linked to cardiopulmonary disease. Tissue-resident (TR) alveolar macrophages (AΦ) are long-lived, self-renew and critical to the health impact of inhalational insults. There is an inadequate understanding of the impact of PM(2.5) ex...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Gangwar, Roopesh Singh, Vinayachandran, Vinesh, Rengasamy, Palanivel, Chan, Ricky, Park, Bongsoo, Diamond-Zaluski, Rachel, Cara, Elaine Ann, Cha, Anthony, Das, Lopa, Asase, Courteney, Maiseyeu, Andrei, Deiuliis, Jeffrey, Zhong, Jixin, Mitzner, Wayne, Biswal, Shyam, Rajagopalan, Sanjay
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462977/
https://ncbi.nlm.nih.gov/pubmed/32873817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71144-1
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