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What is the true discharge rate and pattern of the striatal projection neurons in Parkinson’s disease and Dystonia?

Dopamine and striatal dysfunctions play a key role in the pathophysiology of Parkinson’s disease (PD) and Dystonia, but our understanding of the changes in the discharge rate and pattern of striatal projection neurons (SPNs) remains limited. Here, we recorded and examined multi-unit signals from the...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Valsky, Dan, Heiman Grosberg, Shai, Israel, Zvi, Boraud, Thomas, Bergman, Hagai, Deffains, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462612/
https://ncbi.nlm.nih.gov/pubmed/32812870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57445
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