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β-catenin and γ-catenin are dispensable for T lymphocytes and AML leukemic stem cells

The β-catenin transcriptional coregulator is involved in various biological and pathological processes; however, its requirements in hematopoietic cells remain controversial. We re-targeted the Ctnnb1 gene locus to generate a true β-catenin-null mutant mouse strain. Ablation of β-catenin alone, or i...

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Foilsithe in:eLife
Main Authors: Zhao, Xin, Shao, Peng, Gai, Kexin, Li, Fengyin, Shan, Qiang, Xue, Hai-Hui
Formáid: Artigo
Teanga:Inglês
Foilsithe: eLife Sciences Publications, Ltd 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462606/
https://ncbi.nlm.nih.gov/pubmed/32820720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55360
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