Melatonin Enhances the Therapeutic Effect of Plasma Exosomes Against Cerebral Ischemia-Induced Pyroptosis Through the TLR4/NF-κB Pathway

INTRODUCTION: Ischemic stroke-induced inflammation and inflammasome-dependent pyroptotic neural death cause serious neurological injury. Nano-sized plasma exosomes have exhibited therapeutic potential against ischemia and reperfusion injury by ameliorating inflammation. To enhance its therapeutic po...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Wang, Kankai, Ru, Junnan, Zhang, Hengli, Chen, Jiayu, Lin, Xiao, Lin, Zhongxiao, Wen, Min, Huang, Lijie, Ni, Haoqi, Zhuge, Qichuan, Yang, Su
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461850/
https://ncbi.nlm.nih.gov/pubmed/33013286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00848
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