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Missense Mutations of Human Hsp60: A Computational Analysis to Unveil Their Pathological Significance

Two chaperonopathies have been linked to mutations in the human hsp60 (hHsp60; HSPD1) gene, but other existing variants might cause diseases, even if there is no comprehensive information about this possibility. To fill this vacuum, which might be at the basis of misdiagnoses or simply ignorance of...

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Bibliografische gegevens
Gepubliceerd in:Front Genet
Hoofdauteurs: Vitale, Alessandra Maria, Conway de Macario, Everly, Alessandro, Riccardo, Cappello, Francesco, Macario, Alberto J. L., Marino Gammazza, Antonella
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461820/
https://ncbi.nlm.nih.gov/pubmed/33014020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00969
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