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Characterization of Specific Ion Effects on PI(4,5)P(2) Clustering: Molecular Dynamics Simulations and Graph-Theoretic Analysis

Numerous cellular functions mediated by PI(4,5)P(2) (PIP(2)) involve clustering of the lipid as well as co-localization with other lipids. Although the cation-mediated electrostatic interaction is regarded as the primary clustering mechanism, the ion-specific nature of the intermolecular network for...

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Pubblicato in:J Phys Chem B
Autori principali: Han, Kyungreem, Gericke, Arne, Pastor, Richard W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461730/
https://ncbi.nlm.nih.gov/pubmed/31994887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b10951
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