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Directed Blocking of TGF-β Receptor I Binding Site Using Tailored Peptide Segments to Inhibit its Signaling Pathway
BACKGROUND: TGF-β isoforms play crucial roles in diverse cellular processes. Therefore, targeting and inhibiting TGF-β signaling pathway provides a potential therapeutic opportunity. TGF-β isoforms bind and bring the receptors (TβRII and TβRI) together to form a signaling complex in an ordered manne...
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| Опубликовано в: : | Iran J Biotechnol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Institute of Genetic Engineering and Biotechnology
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7461711/ https://ncbi.nlm.nih.gov/pubmed/32884960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.30498/IJB.2020.197161.2561 |
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