Eplet Mismatch Load and De Novo Occurrence of Donor-Specific Anti-HLA Antibodies, Rejection, and Graft Failure after Kidney Transplantation: An Observational Cohort Study

BACKGROUND: In kidney transplantation, evaluating mismatches of HLA eplets—small patches of surface-exposed amino acids of the HLA molecule—instead of antigen mismatches might offer a better approach to assessing donor-recipient HLA incompatibility and improve risk assessment and prediction of trans...

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Veröffentlicht in:J Am Soc Nephrol
Hauptverfasser: Senev, Aleksandar, Coemans, Maarten, Lerut, Evelyne, Van Sandt, Vicky, Kerkhofs, Johan, Daniëls, Liesbeth, Driessche, Marleen Vanden, Compernolle, Veerle, Sprangers, Ben, Van Loon, Elisabet, Callemeyn, Jasper, Claas, Frans, Tambur, Anat R., Verbeke, Geert, Kuypers, Dirk, Emonds, Marie-Paule, Naesens, Maarten
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2020
Schlagworte:
Clinical Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461684/
https://ncbi.nlm.nih.gov/pubmed/32764139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020010019
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