Revisiting the Amyloid Cascade Hypothesis: From Anti-Aβ Therapeutics to Auspicious New Ways for Alzheimer’s Disease

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder related to age, characterized by the cerebral deposition of fibrils, which are made from the amyloid-β (Aβ), a peptide of 40–42 amino acids. The conversion of Aβ into neurotoxic oligomeric, fibrillar, and protofibrillar assemb...

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Spremljeno u:
Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Uddin, Md. Sahab, Kabir, Md. Tanvir, Rahman, Md. Sohanur, Behl, Tapan, Jeandet, Philippe, Ashraf, Ghulam Md, Najda, Agnieszka, Bin-Jumah, May N., El-Seedi, Hesham R., Abdel-Daim, Mohamed M.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Review
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461598/
https://ncbi.nlm.nih.gov/pubmed/32824102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165858
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