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Controlled Drug Release and Cytotoxicity Studies of Beta-Lapachone and Doxorubicin Loaded into Cyclodextrins Attached to a Polyethyleneimine Matrix

This work presents a new look at the application of cyclodextrins (CD) as a drug nanocarrier. Two different cyclodextrins (αCD, βCD) were covalently conjugated to branched polyethylenimine (PEI), which was additionally functionalized with folic acid (PEI-βCD-αCD-FA). Here, we demonstrated that the c...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kowalczyk, Agata, Kasprzak, Artur, Poplawska, Magdalena, Ruzycka, Monika, Grudzinski, Ireneusz P., Nowicka, Anna M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461587/
https://ncbi.nlm.nih.gov/pubmed/32823816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165832
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