Dermal Fibroblasts Internalize Phosphatidylserine-Exposed Secretory Melanosome Clusters and Apoptotic Melanocytes

Pigmentation in the dermis is known to be caused by melanophages, defined as melanosome-laden macrophages. In this study, we show that dermal fibroblasts also have an ability to uptake melanosomes and apoptotic melanocytes. We have previously demonstrated that normal human melanocytes constantly sec...

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Publicat a:Int J Mol Sci
Autors principals: Ando, Hideya, Yoshimoto, Satoshi, Yoshida, Moemi, Shimoda, Nene, Tadokoro, Ryosuke, Kohda, Haruka, Ishikawa, Mami, Nishikata, Takahito, Katayama, Bunpei, Ozawa, Toshiyuki, Tsuruta, Daisuke, Mizutani, Ken-ichi, Yagi, Masayuki, Ichihashi, Masamitsu
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461560/
https://ncbi.nlm.nih.gov/pubmed/32806720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165789
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