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Metabolic and Molecular Mechanisms of Macrophage Polarisation and Adipose Tissue Insulin Resistance

Inflammation plays a key role in the development and progression of type-2 diabetes (T2D), a disease characterised by peripheral insulin resistance and systemic glucolipotoxicity. Visceral adipose tissue (AT) is the main source of inflammation early in the disease course. Macrophages are innate immu...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Orliaguet, Lucie, Ejlalmanesh, Tina, Alzaid, Fawaz
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7460862/
https://ncbi.nlm.nih.gov/pubmed/32785109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165731
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