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Development of CRISPR Interference (CRISPRi) Platform for Metabolic Engineering of Leuconostoc citreum and Its Application for Engineering Riboflavin Biosynthesis

Leuconostoccitreum, a hetero-fermentative type of lactic acid bacteria, is a crucial probiotic candidate because of its ability to promote human health. However, inefficient gene manipulation tools limit its utilization in bioindustries. We report, for the first time, the development of a CRISPR (Cl...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Son, Jaewoo, Jang, Seung Hoon, Cha, Ji Won, Jeong, Ki Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7460652/
https://ncbi.nlm.nih.gov/pubmed/32764465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165614
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