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First Total Synthesis of 5′-O-α-d-Glucopyranosyl Tubercidin

The first total synthesis of 5′-O-α-d-glucopyranosyl tubercidin was successfully developed. It is a structurally unique disaccharide 7-deazapurine nucleoside exhibiting fungicidal activity, and was isolated from blue-green algae. The total synthesis was accomplished in eight steps with 27% overall y...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mar Drugs
Hauptverfasser: Ouyang, Wenliang, Huang, Haiyang, Yang, Ruchun, Ding, Haixin, Xiao, Qiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459636/
https://ncbi.nlm.nih.gov/pubmed/32751067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md18080398
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