In-Vitro Identification and In-Vivo Confirmation of DNA Methylation Biomarkers for Urothelial Cancer

We identified DNA methylation targets specific for urothelial cancer (UC) by genome-wide methylation difference analysis of human urothelial (RT4, J82, 5637), prostate (LNCAP, DU-145, PC3) and renal (RCC-KP, CAKI-2, CAL-54) cancer cell lines with their respective primary epithelial cells. A large ov...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Köhler, Christina U., Walter, Michael, Lang, Kerstin, Plöttner, Sabine, Roghmann, Florian, Noldus, Joachim, Tannapfel, Andrea, Tam, Yu Chun, Käfferlein, Heiko U., Brüning, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459535/
https://ncbi.nlm.nih.gov/pubmed/32707764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8080233
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