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Donor strand sequence, rather than donor strand orientation, determines the stability and non-equilibrium folding of the type 1 pilus subunit FimA

FimA is the main structural subunit of adhesive type 1 pili from uropathogenic Escherichia coli strains. Up to 3000 copies of FimA assemble to the helical pilus rod through a mechanism termed donor strand complementation, in which the incomplete immunoglobulin-like fold of each FimA subunit is compl...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zyla, Dawid, Echeverria, Blanca, Glockshuber, Rudi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458822/
https://ncbi.nlm.nih.gov/pubmed/32651228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014324
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