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Turning tolerogenic into immunogenic ileal cell death through ileal microbiota: the key to unlock the mystery of colon cancer immunoscore?

Why PD-1 blockade is ineffective in the vast majority of colorectal cancers (CCs) lacking microsatellite instability but harboring high densities of tumor infiltrating T cells and follicular T helper (TFH) and B cells remained so far an open conundrum. In a recent report published in Nature Medicine...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Roberti, Maria Paula, Picard, Marion, Yonekura, Satoru, Zitvogel, Laurence
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458629/
https://ncbi.nlm.nih.gov/pubmed/32923141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1778834
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