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FOXK1 Participates in DNA Damage Response by Controlling 53BP1 Function
53BP1 plays a central role in dictating DNA repair choice between non-homologous end joining (NHEJ) and homologous recombination (HR), which is important for the sensitivity to poly(ADP-ribose) polymerase inhibitors (PARPis) of BRCA1-deficient cancers. In this study, we show that FOXK1 associates wi...
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| Veröffentlicht in: | Cell Rep |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7458625/ https://ncbi.nlm.nih.gov/pubmed/32783940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108018 |
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