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Mineralization of pH-Sensitive Doxorubicin Prodrug in ZIF-8 to Enable Targeted Delivery to Solid Tumors

[Image: see text] The zeolitic imidazolate framework (ZIF-8), composed of zinc ion and dimethylimidazole, is widely used in drug delivery because of the easy fabrication process and the good biosafety. However, ZIF-8 suffers from low affinity to nonelectric-rich drugs and does not have surface funct...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Yan, Jiaqi, Liu, Chang, Wu, Qiwei, Zhou, Junnian, Xu, Xiaoyu, Zhang, Lirong, Wang, Dongqing, Yang, Fan, Zhang, Hongbo
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458362/
https://ncbi.nlm.nih.gov/pubmed/32664723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c02599
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