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Frameshift Mutations and Loss of Expression of CLCA4 Gene are Frequent in Colorectal Cancers With Microsatellite Instability

Chloride channel calcium-activated (CLCA) genes encode regulators for chloride transport across the cell membrane. As for cancer development, some CLCA genes are considered putative tumor suppressor genes. The aim of this study was to explore whether CLCA4 gene would have mutations in its nucleotide...

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Veröffentlicht in:Appl Immunohistochem Mol Morphol
Hauptverfasser: Mo, Ha Yoon, Lee, Ju Hwa, Kim, Min Sung, Yoo, Nam Jin, Lee, Sug Hyung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458082/
https://ncbi.nlm.nih.gov/pubmed/32773719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAI.0000000000000777
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