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Multi-level consistent changes of the ECM pathway identified in a typical keratoconus twin’s family by multi-omics analysis

BACKGROUND: Keratoconus (KC) is a common, degenerative disorder of the cornea, and genetic factors play a key role in its development. However, the genetic etiology of KC is still unclear. This study used the family of twins as material, using, for the first time, multi-omics analysis, to systematic...

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Dades bibliogràfiques
Publicat a:Orphanet J Rare Dis
Autors principals: Hao, Xiao-dan, Chen, Xiu-nian, Zhang, Yang-yang, Chen, Peng, Wei, Chao, Shi, Wei-yun, Gao, Hua
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457807/
https://ncbi.nlm.nih.gov/pubmed/32867823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-020-01512-7
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