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Cancer-derived exosomal TRIM59 regulates macrophage NLRP3 inflammasome activation to promote lung cancer progression

BACKGROUND: Exosomes are emerging as important mediators of the cross-talk between tumor cells and the microenvironment. The communication between tumor-derived exosomes and macrophages has a critical role in facilitating tumor progression. However, the mechanisms by which exosomes modulate tumor de...

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Библиографические подробности
Опубликовано в: :J Exp Clin Cancer Res
Главные авторы: Liang, Manman, Chen, Xingwu, Wang, Lijing, Qin, Lilong, Wang, Hanli, Sun, Zhengui, Zhao, Wenying, Geng, Biao
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457778/
https://ncbi.nlm.nih.gov/pubmed/32867817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01688-7
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