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Akt regulates a Rab11-effector switch required for ciliogenesis

Serum starvation stimulates cilia growth in cultured cells, yet, serum factors associated with ciliogenesis are unknown. Previously, we showed that starvation induces rapid Rab11-dependent vesicular trafficking of Rabin8, a Rab8 GEF, to the mother centriole leading to Rab8 activation and cilium grow...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Walia, Vijay, Cuenca, Adrian, Vetter, Melanie, Insinna, Christine, Perera, Sumeth, Lu, Quanlong, Ritt, Daniel A., Semler, Elizabeth, Specht, Suzanne, Stauffer, Jimmy, Morrison, Deborah K., Lorentzen, Esben, Westlake, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457226/
https://ncbi.nlm.nih.gov/pubmed/31204173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.05.022
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