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Cholinergic White Matter Lesions, AD-Signature Cortical Thickness, and Change in Cognition: The Northern Manhattan Study

BACKGROUND: How cerebrovascular disease and neurodegeneration affect each other to impact cognition is not yet known. We aimed to test whether Alzheimer’s disease-signature (AD) cortical thickness mediates the association between cholinergic white matter lesion load and change in domain-specific cog...

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Publicat a:J Gerontol A Biol Sci Med Sci
Autors principals: Caunca, Michelle R, Siedlecki, Karen, Cheung, Ying Kuen, Alperin, Noam, Lee, Sang H, Elkind, Mitchell S V, Sacco, Ralph L, Wright, Clinton B, Rundek, Tatjana
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457185/
https://ncbi.nlm.nih.gov/pubmed/31944231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glz279
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