Dasatinib Inhibits Lyn and Fyn Src-Family Kinases in Mast Cells to Suppress Type I Hypersensitivity in Mice

Mast cells (MCs) are systemically distributed and secrete several allergic mediators such as histamine and leukotrienes to cause type I hypersensitivity. Dasatinib is a type of anti-cancer agent and it has also been reported to inhibit human basophils. However, dasatinib has not been reported for it...

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Publicado en:Biomol Ther (Seoul)
Main Authors: Lee, Dajeong, Park, Young Hwan, Lee, Ji Eon, Kim, Hyuk Soon, Min, Keun Young, Jo, Min Geun, Kim, Hyung Sik, Choi, Wahn Soo, Kim, Young Mi
Formato: Artigo
Idioma:Inglês
Publicado: The Korean Society of Applied Pharmacology 2020
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457176/
https://ncbi.nlm.nih.gov/pubmed/32268657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2020.013
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