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RNA Interference Characterization of Proteins Discovered by Proteomic Analysis of Pancreatic Cancer Reveals Function in Cell Growth and Survival

OBJECTIVES: There is a clear need for better therapeutics and diagnostics for pancreatic cancer. We aimed to discover plasma membrane-associated proteins overexpressed in pancreatic cancer using quantitative proteomics and apply RNA interference (RNAi) to uncover proteins associated with cancer cell...

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Detalhes bibliográficos
Publicado no:Pancreas
Main Authors: Lee, Candy N., Heidbrink, Jenny L., McKinnon, Katherine, Bushman, Victoria, Olsen, Henrik, FitzHugh, William, Li, Aiqun, Van Orden, Karen, He, Tao, Ruben, Steven M., Moore, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457147/
https://ncbi.nlm.nih.gov/pubmed/21934552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e3182236385
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