Systematic Review and Meta-Analysis of Correlation of Progression-Free Survival-2 and Overall Survival in Solid Tumors

Background: Using progression-free survival (PFS)2, time from randomization to 2nd disease progression or death, is proposed as a surrogate for overall survival (OS) in oncology clinical trials. We used published data from solid tumor trials to assess whether PFS2 and OS are correlated. Methods: A l...

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Publicat a:Front Oncol
Autors principals: Chowdhury, Simon, Mainwaring, Paul, Zhang, Liangcai, Mundle, Suneel, Pollozi, Eneida, Gray, Alexander, Wildgust, Mark
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456898/
https://ncbi.nlm.nih.gov/pubmed/32923387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01349
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